Cemento-ossifying fibroma is classified as an osteogenic tumor, defined as a well -differentiated tumor, occasionally encapsulated, comprising fibrous tissue. Abstract. Introduction: Cemento-ossifying fibroma is a benign fibro-osseous maxillary tumor belonging to the same category as fibrous dysplasia and. Background: Cemento-Ossifying Fibroma (COF) is considered by most as relatively rare, benign, non-odontogenic neoplasm of the jaw bones and other.

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In the early stages, COF may appear as unilocular or multilocular radiolucent lesion and as the lesion matures, they may transform ribroma a radiopaque one, resulting in a lesion with mixed density.

The cemento-ossifying fibroma is classified as a fibro-osseous lesion of the jaws. The extent to which the tumor spreads, guides surgical therapy.

Subscribe to Table of Contents Alerts. Excessive proliferation of mature fibrous connective tissue is a response to gingival injury, gingival irritation, subgingival calculus, or a foreign body in the gingival sulcus.

However, in recent years, the presentation of microscopically indistinguishable lesions in the frontal, temporal, sphenoid, and ethmoid bones disputes the above assumption.

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Malkunje Open Journal of Stomatology. Peripheral cemento-ossifying fibroma of maxilla. Although peripheral ossifying fibroma is benign, reactive lesion, the recurrence rate is fairly high. X-ray diffraction analysis indicated that the mineral phase of both central and peripheral tissues consists of apatite crystals and that the crystallinity of the apatites might improve progressively with the development of the lesion, possibly to the same degree as that of bone apatite [ 16 ].

The patient was apparently asymptomatic 18 months back when he developed a small swelling in the mandibular anterior labial region in 31, 41 which gradually increased in size. The hybrid term central cementoossifying fibroma was thus adopted to indicate the likely presence of both types of tissue within the same lesion and because of the difficulty in differentiating reliably between immature bone and immature cementum.


The lesion is invariably encapsulated and of mixed radiolucent densities. July 04, Citation: Unable to process the form. An interdisciplinary approach is required [ 14 ] to diagnose a COF from clinical, radiographic and microscopic features. Larger lesions with size over 80 mm in their greatest diameter have been termed as giant ossifying fibroma [ 7 ]. Cementoossifying fibroma is considered by most as relatively rare, benign, nonodontogenic neoplasm of the jaw bone.

Ostrosky The Journal of Prosthetic Dentistry. J Int Acad Periodontol. Agri and Aquaculture Journals Dr.

The internal structure of the lesion was mainly radiolucent, with diffuse scattered radiopacity. National Center for Biotechnology InformationU. The present case shows all the features related to cement-ossifying cemsnto whose aetiology is of unknown origin and added one more incidence of COF and will be helpful in the literature.

Cemento-ossifying fibroma of the mandible

Ear Nose Throat J. Cakir B, Karadayi N. The swelling was gradually increasing in size. J Clin Exp Dent. No history of previous similar swelling, toothache, or numbness could be elicited. The latter is also known as peripheral cementifying fibroma, ossifying fibro-epithelial polyp, peripheral fibroma with calcification, calcifying fibroblastic granuloma.

Support Center Support Center. To view the erratum, please click here. Due to the good delimitation of the tumor, surgical removal and curettage is also a treatment of choice. Edit article Share article View revision history. Case 3 Case 3. POF is a slowly progressing lesion, the growth of which is generally limited. Few authors have considered that these lesions arose either by reactive or developmental origin, from the periodontal membrane which contains multi-potential cells, that under certain pathologic conditions, are capable of producing tumours which are composed of cementum, oswifying bone or fibrous tissue [ 9 ].


Facial asymmetry of the right side with a well-defined dome-shaped swelling over the right body of mandible. The cemento-ossifying fibroma is a central neoplasm of bone as well as periodontium which has caused considerable controversy because of confusion regarding terminology and the criteria for its diagnosis.

Pain aggravates on chewing food, on taking any hot and cold fluids and issifying on its own after sometime. Log in Sign up.

Peripheral cemento-ossifying fibroma is a relatively rare tumour classified between fibroosseous lesions. They expand the surrounding cortical bone without cortical perforation, while cemenot a spherical shape and may result in tooth divergence and resorption. Please review our privacy policy.

Cemento-ossifying fibroma of the mandible

The diagnosis of cemento-ossifying fibroma of the jaw can be established based on clinical, radiographic and histo-pathological features.

Examination revealed approximately pedunculated nontender, firm, pinkish red growth present on the buccal gingival in relation to maxillary right canine to 1st molar.

The concept of fibroosseous lesions of bone has evolved over the last several decades and now includes two major entities: Case Report Open Access.

When bone and cementum-like tissues are observed, the lesions have been referred to as cemento-ossifying fibroma [ 11 ].