Diagnostic de l’intoxication digitalique et son traitement. Ferrero C. Author affiliations. Clinique universitaire de Médecine Interne, Hôpital Cantonal, Genève . Request PDF on ResearchGate | Intoxication digitalique en période néonatale: rôle de la déshydratation | Background Despite the great progress which has. Request PDF on ResearchGate | Intoxication digitalique massive. Traitement par hémoperfusion sur résine Amberlite XAD 4 | Haemoperfusion over amberlite.

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Drug interaction Mechanism and consequence of interaction All hypokalemic drugs diuretics, laxatives, corticosteroids, amphotericin B Increased toxicity of digitalis Calcium by injection Increased toxicity of digitalis Phenobarbital phenytoin Decreased plasma concentrations Table 2: Digitalis intoxication shows itself in electrocardiogram ECG abnormalities that can lead to arrhythmia potentially digotalique and in different signs and symptoms that are not specific.

The next sodic influx. Phenytoin diphenylhydantoin treatment of massive digoxin overdose. Patients with severe renal impairment should be the subject of a prolonged follow up because it is not known with certainty if the inability to eliminate the antibody complex-digoxin may translate into a liberation of digoxin [6]. Conduction disturbances Can be very early stage with a risk of evolution of severe bradycardia or even an asystole. This text will be overwritten by jQuery.


Journal List Br Heart J v. Please review our privacy policy.

You can move this window by clicking on the headline. Electrophysiological action At therapeutic concentrations, the digitalis glycosides decrease automaticity and slow atrioventricular conduction. Am J Cardiol Neurosensorial disorders Approximately one quarter of the patients suffer in early stages from clouding of consciousness, somnolence or restlessness with anguish. The recommended therapeutical concentrations are of 0.

The dose depends on the quantity of digoxin present in the body.

Disorders of impulse conduction and impulse formation caused by hyperkalemia in man. Digoxin immune Fab therapy in the management of digitalis intoxication: The digoxin is administrated in a single daily take. The clinical presentation of acute intoxication differs a little from that of a chronic intoxication.

Médecine thérapeutique

The treatment consists of electrolytic controls, supplements when needed and anti-arrhythmic agents if there is a significant presence of dysrhythmias. Cardiac manifestations Responsible for all the prognosis of digitalis intoxication, whatever it might be acute or chronic. Correlation of serum magnesium levels and cardiac digitalis digitaliqeu. Review of the literature.

Acute digitalis intoxication bringing into play the prognosis for survival is a rare complication in children, particularly in the neonatal period. Atropine administration must be taken into account in case of sinus bradycardia or atrioventricular block AV of the second and third degree to correct the effects of vagal stimulation.


Despite being very familiar with digitalis, its use always asks for particular attention. Access to the PDF text.

Intoxication Digitalique

Despite our great familiarity with this molecule, its use requires a special attention since it has a narrow therapeutic index [1]. Digitaliqus Help Who are we? A second Antidote dose is founded at the onset of clinical signs associated with a pejorative factor Table 4. Nouv Presse Med It is recalled that the signs of glycosides digitalis impregnations may manifest at therapeutical doses.

The digitalis glycosides constitute a homogeneous group of cardiotonics glycosides with different pharmacokinetic properties, digoxin is digitallique digitalis currently used. Effect of ouabain and its interaction with diphenylhydantoin on cardiac arrhythmias induced by hypothalamic stimulation.

Intensive Care Med